COGNITONEXTGEN

Project Detail

Use case 1:

Enhancing Clinical Trial Dashboards with Machine Learning

Main Objective:

Enhance the existing Clinical Trial Dashboards by incorporating machine learning models. The machine learning models will be used to predict future outcomes, such as the likelihood of a patient dropping out of the trial or experiencing a serious adverse event (SAE).

Business Problem

Prescriptive Insights: Provide recommendations based on the predictions, such as adjusting the treatment plan for a patient at high risk of dropping out.

Patient Clustering: Group patients based on their similar characteristics or phenotypes.

Learning from Past Data: Learn from their historical trial data and gain insights into patient populations at higher risk.

Solution Highlights

AE Profiles: Captures patient history of
adverse events.

Likelihood Prediction: The AE profiles are used to predict the likelihood of a patient’s future dropout based on the identified susceptible phenotypes.

Train a classifier for drop out on historic
data that can predict well on ongoing
studies

Tools and Technologies

● Python
● Tableau
● AI/ML Model (Auto ML)
● Generative AI (Gemini)

Business Benefits:

Enhanced Patient Experience: Personalized care and reduced burden on patients.

Visuals on weekly drop-out
prediction, post each visit data collection with patient level details

Alert for patients in high-risk clusters and with high likelihood of drop out

Reduced Costs: Minimize
trial failures and associated
expenses.

Use case 2:

Gen AI-Powered Conversational Agent for Patient-Reported Outcomes

Main Objective:

To develop a Gen AI-based conversational agent (chatbot) to interact with patients, to gather the comprehensive set of measures such as Physical function, sleep disorder,fatigue etc. to standardize the assessment of patient-reported outcomes across different health conditions and automatically fill out the form.

Business Problem

Improve the efficiency and engagement of their offline pre-medical questionnaire
process.

Patients find it difficult to complete lengthy questionnaires.

Lack of standardization in PROMIS 29 data collection hinders comparative analysis and research.

Solution Highlights

Efficiency: Automated data collection reduces administrative burden and
improves efficiency.

Accuracy: AI-powered conversational agents ask personalized questions for
consistent and accurate data capture.

Patient Experience: A conversational interface provides a more engaging and user-friendly experience for patients.

Tools and Technologies

● Python
● Gemini Pro 1.5
● BigQuery

Business Benefits:

Improved Decision Making:
Accurate and standardized data
collection.

Reduced Costs:  Automation help to reduce operational costs associated with data collection.

Increased Patient Satisfaction: A more efficient and engaging patient experience

Use case 3:

Evaluating Gen AI-Generated Literature Summaries

Main Objective:

Determine the potential for Gen AI to augment or replace human summarization tasks. Assess the quality and accuracy of Gen AI-generated summaries compared to human-generated summaries.

Business Problem

Human-generated summaries are time-consuming and inconsistent.

Scalable and efficient solution to summarize large volumes of text.

The quality of summaries vary depending on the expertise and experience of the human summarizer.

Solution Highlights

Efficiency: Gen AI can generate
summaries quickly and efficiently.

Consistency: Maintain a consistent style and tone for AI generated summaries,

Handle large volumes of text without compromising quality.

Tools and Technologies

● AI Act
● GAMP 5 Compliance Guideline comparison
● AI Act comparison with SOPs
● GPT-3, Azure Cosmos DB, Elastic Search

Business Benefits:

Reduced reliance on human summarizers can lead to cost savings.
Improved Productivity: Faster and more efficient summarization can increase productivity.
Drive innovation in content creation and analysis.

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